Dimethyl Sulfoxide
Apexbio Technology LLC Eptifibatide 188627-80-7 10mM (in 1mL DMSO)
Eptifibatide is a cyclic heptapeptide belonging to the glycoprotein IIb/IIIa inhibitor category functioning as an antagonist of platelet adhesion by reversibly binding to the platelet glycoprotein IIb/IIIa receptor This receptor located on platelet surfaces mediates platelet aggregation through binding fibrinogen and von Willebrand factor processes essential in thrombus formation By blocking the GP IIb/IIIa receptor binding site Eptifibatide inhibits fibrinogen-dependent platelet cross-linking reducing platelet aggregation In biomedical research Eptifibatide serves as a pharmacological tool to investigate platelet function thrombosis mechanisms and related cardiovascular diseases in preclinical and clinical models
Apexbio Technology LLC Protionamide 14222-60-7 10mM (in 1mL DMSO)
Protionamide is a thiophene-derived antibacterial compound that inhibits the synthesis of mycolic acids a major component of the mycobacterial cell wall Through disruption of mycolic acid biosynthesis it interferes with cell wall integrity exhibiting antibacterial activity against pathogenic mycobacteria Protionamide is commonly employed in research involving Mycobacterium tuberculosis and Mycobacterium leprae primarily for investigating molecular mechanisms underlying drug resistance and cell wall biosynthesis pathways In laboratory experiments this compound is frequently utilized in vitro for cultivation assays antimicrobial screening and studies on synergistic effects when combined with other antimycobacterial agents It demonstrates reported IC50 values in the micromolar range dependent on experimental conditions and mycobacterial strains used
Medchemexpress LLC IRG1 IN 1 10 MM 1 ML IN DMSO
IRG1-IN-1 10 mM 1 mL in DMSO ready for reconstitution
Medchemexpress LLC Jsh-23 10Mm 1Ml Dmso Solution | HY-13982-10MM 1ML DMSO
Jsh-23 10Mm 1Ml Dmso Solution
Medchemexpress LLC XMU-MP-9 ,10 mM 1 mL in DMSO Solution
XMU-MP-9 is a bifunctional compound that binds to the C2 domain of Nedd4-1 and the allosteric site of K-Ras. XMU-MP-9 enhances the interaction between Nedd4-1 and K-Ras, induces conformational changes in the Nedd4-1/K-Ras complex, promotes the ubiquitination and degradation of multiple K-Ras mutants, and inhibits the proliferation of cells carrying K-Ras mutants. XMU-MP-9 can be used in cancer research.
Selleck Chemical LLC Trametinib DMSO solvate S4484-100mg
Trametinib DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0 92 nM/1 8 nM in cell-free assay Trametinib activates autophagy and induces apoptosis
Apexbio Technology LLC Z-YVAD-FMK 210344-97-1 10mM (in 1mL DMSO)
Z-YVAD-FMK (CAS 210344-97-1) is a cell-permeable irreversible inhibitor of caspase-1 By inhibiting caspase-1 activity it interferes with caspase-mediated signaling cascades involved in cell apoptosis and cytokine maturation In Caco-2 cells Z-YVAD-FMK reduces butyrate-induced growth inhibition and fully abrogates butyrate s effects at 100 mol/L Additionally in MyD88-deficient murine bone marrow dendritic cells Z-YVAD-FMK effectively blocks alum-induced caspase-1 activation and subsequent IL-1 release It serves as a valuable research tool for investigating caspase-dependent apoptotic pathways and inflammatory responses
Sigma Aldrich Fine Chemicals Biosciences Dimethyl sulfoxide suitabl
Dimethyl sulfoxide (DMSO) is a polar organic solvent. DMSO activated by various electrophiles (oxalyl chloride) has been used to oxidize various alcohols (primary secondary allylic benzylic hindered and bicyclic). Carbonyl compounds are formed as reaction products. Due to its higher stability it has been proposed as an alternate solvent for methyl cellosolve for use in ninhydrin reaction.
