Dimethyl Sulfoxide
Crescent Chemical Co Inc DIMETHYL SULFOXIDE
Dimethyl sulfoxide research grade Highly active solvent and pharmaceutical vehicle; for freezing cells. For gradient centrifugation (1). Determination of cysteine and cystine in proteins (2). Size - 250ML Storage Conditions - +15 °C TO +30 °C Catalog
Medchemexpress LLC Puromycin 10 Mm 1 Ml In Dmso | HY-B1743-10 MM 1 ML IN
Puromycin 10 Mm 1 Ml In Dmso
Medchemexpress LLC Ly2090314 1Ml Dmso Reconstitut | HY-16294-1ML DMSO RECONST
Ly2090314 1Ml Dmso Reconstitut
Medchemexpress LLC Ru.521 10Mm Dmso Solid 1Nl | HY-114180-10MM DMSO SOLID
Ru.521 10Mm Dmso Solid 1Nl
Apexbio Technology LLC AGN 194310 229961-45-9 10mM (in 1mL DMSO)
AGN 194310 is a pan-retinoic acid receptor (RAR) antagonist with affinity for RAR RAR and RAR It binds these receptors with Kd values of 3 nM 2 nM and 5 nM respectively By competing with RAR agonists AGN 194310 blocks receptor-mediated cellular responses In cell-based assays AGN 194310 inhibits the proliferation and colony formation of prostate carcinoma cell lines (LNCaP PC3 DU-145) induces G1 cell cycle arrest and promotes apoptosis In addition it suppresses agonist-induced differentiation in HL60 cells AGN 194310 serves as a research tool to investigate RAR-driven signaling pathways and tumor cell growth mechanisms particularly in oncology studies examining retinoid receptor functions
Cayman Chemical L-MethIonIn SulfoxIde 25g
A sulfoxide-modified methionine; increases weight gain in weanling mice in the diet at 6.3, 12.6, and 18.9 mmol/g; levels are decreased in patients with vitiligo
Apexbio Technology LLC Carprofen 53716-49-7 10mM (in 1mL DMSO)
Carprofen (CAS 53716-49-7) is a non-steroidal anti-inflammatory drug (NSAID) primarily characterized by selective inhibition of cyclooxygenase-2 (COX-2) This selective targeting leads to decreased prostaglandin synthesis mitigating inflammation and pain responses In assays involving canine COX-2 enzyme carprofen exhibits inhibitory activity with an IC50 value of approximately 0 03 mM Due to its targeted COX-2 inhibition carprofen serves as a useful research compound in veterinary and biomedical studies investigating inflammatory pathways and analgesic mechanisms
Apexbio Technology LLC GMX1778 (CHS828) 200484-11-3 10mM (in 1mL DMSO)
GMX1778 (CHS828 CAS 200484-11-3) is a small-molecule inhibitor targeting nicotinamide phosphoribosyltransferase (NAMPT) an enzyme crucial for NAD biosynthesis with a reported Kd value of 120 nM NAD functions as a cofactor essential for enzymatic oxidation-reduction processes and diverse cellular events including metabolism genomic integrity calcium signaling aging and apoptosis In cultured IM-9 cells exposure to GMX1778 substantially decreases NAD and NM levels in a time-dependent manner GMX1778 displays anti-tumor activity preferentially in NAPRT1-deficient cancer models highlighting its potential utility for investigating metabolic vulnerabilities and targeted cancer therapies
Apexbio Technology LLC Apatinib 10mM (in 1mL DMSO)
B2303 is a synthetic small molecule designed for biomedical research acting primarily as an inhibitor targeting specific intracellular signaling pathways involved in cell proliferation and survival It modulates intracellular signaling cascades implicated in pathological conditions such as inflammation cancer progression and aberrant cell growth B2303 serves as a molecular probe suitable for investigating intracellular processes and as a tool for dissecting signal transduction mechanisms enabling researchers to explore therapeutic targets for various diseases
Sigma Aldrich Fine Chemicals Biosciences Dimethyl sulfoxide | 67-68-5 | MFCD00002089 | 2.5L
Dimethyl sulfoxide | Purity: ≥99.9% | MW:78.13 | 67-68-5 | MFCD00002089 | 2.5L
Apexbio Technology LLC Canagliflozin(Synonyms: Invokana, TA-7284, JNJ-28431754, Sulisent, Canagliflozin hemihydrate), 10mM (in 1mL DMSO), CAS: 842133-18-0.
Canagliflozin (CAS 842133-18-0) is a selective inhibitor of sodium-glucose cotransporter 2 (SGLT2) a transporter responsible for renal glucose reabsorption By inhibiting SGLT2 activity Canagliflozin decreases renal glucose reabsorption resulting in increased urinary glucose excretion In CHO cells expressing human rat or mouse SGLT2 Canagliflozin potently inhibits sodium-dependent glucose uptake with IC50 values of 4 4 3 7 and 2 0 nM respectively Animal studies using db/db mice and Zucker diabetic fatty (ZDF) rats demonstrate dose-dependent reductions in blood glucose as well as decreased respiratory exchange ratio and body weight Canagliflozin is suitable for in vivo research through oral administration